Harrison Pharmacy Bogor still relies on manual processes to manage drug purchases from distributors, using notebooks and simple documents. This condition causes problems such as slow data retrieval, a high risk of recording errors, and difficulty in preparing purchase reports quickly and accurately. This study aims to design and develop a web-based drug purchasing information system using the Waterfall development method. The system is built with the PHP programming language on the Laravel framework, MySQL as the database, and XAMPP as the local server. The developed system covers the management of distributor data, drug data, ordering, payment, order confirmation, invoice creation, and purchase reports. Black Box Testing results show that all system functions work as expected. The system is expected to improve the efficiency, accuracy, and transparency of the drug purchasing process at Harrison Pharmacy Bogor.